Comment accéder aux bénéfices de la restriction calorique sans se priver ? Grâce aux mimétiques de la restriction calorique. LaNutrition.fr vous présente les principaux candidats à ce titre.
La restriction calorique
De nombreuses études suggèrent qu’en diminuant notre ration quotidienne de calories, on limite le risque de certaines maladies, notamment de diabète, de maladies cardiovasculaires et de cancer. Explications.
Que se passerait-t-il si l’on consommait 20 à 30 % de calories en moins au quotidien ? Nous serions probablement en bien meilleure santé. De nombreuses études suggèrent que la restriction calorique permettrait non seulement de réduire le vieillissement mais également de limiter le risque de nombreuses maladies.
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Références
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Lefevre M, Redman LM, Heilbronn LK, Smith JV, Martin CK, Rood JC, Greenway FL, Williamson DA, Smith SR, Ravussin E; Pennington CALERIE team Caloric restriction alone and with exercise improves CVD risk in healthy non-obese individuals. Atherosclerosis. 2009 Mar;203(1):206-13. Epub 2008 Jul 7.
- Heilbronn LK, de Jonge L, Frisard MI, DeLany JP, Larson-Meyer DE, Rood J, Nguyen T, Martin CK, Volaufova J, Most MM, Greenway FL, Smith SR, Deutsch WA, Williamson DA, Ravussin E; Pennington CALERIE Team. Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. JAMA. 2006 Apr 5;295(13):1539-48.
- R.J. Colman, R.M. Anderson, S.C. Johnson, E.K. Kastman, K.J. Kosmatka, T.M. Beasley, D.B. Allison, C. Cruzen, H.A. Simmons, J.W. Kemnitz, R. Weindruch "Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys" Science 10 July 2009, Volume 325, Pages 201-204
- Leonie K. Heilbronn, et al; for the Pennington CALERIE Team. Effect of 6-Month Calorie Restriction on Biomarkers of Longevity, Metabolic Adaptation, and Oxidative Stress in Overweight Individuals. JAMA. 2006;295:1539-1548.
- Meyer TE, Kovacs SJ, Ehsani AA, Klein S, Holloszy JO, Fontana L. Long-term caloric restriction ameliorates the decline in diastolic function in humans. J Am Coll Cardiol. 2006 Jan 17;47(2):398-402.
- Fontana L, Meyer TE, Klein S, Holloszy JO Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proceedings of the National Academy of Sciences of the U. S. A. 2004 Apr 7; 101(17):6659-63.
- Hursting SD, Smith SM, Lashinger LM, Harvey AE, Perkins SN. Calories and carcinogenesis: lessons learned from 30 years of calorie restriction research. Carcinogenesis. 2010 Jan;31(1):83-9. Epub 2009 Dec
- Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO. Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell. 2008 Oct;7(5):681-7.
- Li Y, Liu L, Tollefsbol TO Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression. FASEB J. 2009 Dec 17
- A. V. Witte, M. Fobker, R. Gellner, S. Knecht, and A. Flöel Caloric restriction improves memory in elderly humans PNAS 2009 106:1255-1260; published online before print January 26, 2009, doi:10.1073/pnas.0808587106
- Wang J, et al. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. FASEB J. 2005 Apr;19(6):659-61. Epub 2005 Jan 13
- Holloszy JO, Fontana L. Caloric restriction in humans. Exp Gerontol. 2007 Aug;42(8):709-12. Epub 2007 Mar 31. Review.
- Kalani R, Judge S, Carter C, Pahor M, Leeuwenburgh C. Effects of caloric restriction and exercise on age-related, chronic inflammation assessed by C-reactive protein and interleukin-6. J Gerontol A Biol Sci Med Sci. 2006 Mar;61(3):211-7.
- Zainal TA, Oberley TD, Allison DB, Szweda LI, Weindruch R. Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle. FASEB J. 2000 Sep;14(12):1825-36.
- Anthony E. Civitarese, Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy Humans, PloS Medicine, march 2007
- Heydari AR, Unnikrishnan A, Lucente LV, Richardson A. Caloric restriction and genomic stability. Nucleic Acids Res. 2007;35(22):7485-96. Epub 2007 Oct 16.
- López-Lluch G, Hunt N, Jones B, Zhu M, Jamieson H, Hilmer S, Cascajo MV, Allard J, Ingram DK, Navas P, de Cabo R. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1768-73. Epub 2006 Jan 30.
- Cantó C, Auwerx J. Caloric restriction, SIRT1 and longevity. Trends Endocrinol Metab. 2009 Sep;20(7):325-31. Epub 2009 Aug 25. Review.
- Anthony E. Civitarese, Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy Humans, PloS Medicine, march 2007.
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