Soigner le syndrome des ovaires polykystiques naturellement

Par Pierre Lombard Publié le 11/05/2016 Mis à jour le 19/04/2021 Edition Abonné
Article

Ce syndrome représente l'une des premières causes d’infertilité des femmes. Lié à des facteurs environnementaux, il peut être amélioré par l’alimentation et certains compléments alimentaires. Détails.

Le syndrome des ovaires polykystiques (SOPK), encore appelé Anovulation Hyperandrogénique (AH), est l’un des désordres hormonaux féminins les plus communs. Il touche  entre 5% et 10% des femmes partout dans le monde (1). C’est la première cause d’infertilité chez les femmes.
Ce syndrome a été...

Références
  1. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004;89:2745-9.
  2. A. Torre, H. Fernandez.  Le syndrome des ovaires polykystiques (SOPK),État des connaissances. Journal de Gynécologie Obstétrique et Biologie de la Reproduction Vol 36, N° 5  - septembre 2007.pp. 423-446. Doi : 10.1016/j.jgyn.2007.04.002
  3. Les femmes ayant des ovaires polykystiques ont plus de chance d’être hospitalisés
  4. Casarini L, Simoni M, Brigante G. Is polycystic ovary syndrome a sexual conflict? A review. Reprod Biomed Online. 2016 Apr;32(4):350-61. doi: 10.1016/j.rbmo.2016.01.011. Epub 2016 Feb 2
  5. Kandaraki E, Chatzigeorgiou A, Livadas S, Palioura E, Economou F, Koutsilieris M, Palimeri S, Panidis D, Diamanti-Kandarakis E. Endocrine disruptors and polycystic ovary syndrome (PCOS): elevated serum levels of bisphenol A in women with PCOS.J Clin Endocrinol Metab. 2011 Mar;96(3):E480-4. doi: 10.1210/jc.2010-1658. Epub 2010 Dec 30.
  6. Tsutsumi O. Assessment of human contamination of estrogenic endocrine-disrupting chemicals and their risk for human reproduction.J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):325-30. Epub 2005 Jan 26.
  7. Takeuchi T, Tsutsumi O, Ikezuki Y, Takai Y, Taketani Y. Positive relationship between androgen and the endocrine disruptor, bisphenol A, in normal women and women with ovarian dysfunction. Endocr J. 2004 Apr;51(2):165-9.
  8. Savastano S et al. Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population.J Transl Med. 2015 May 29;13:169. doi: 10.1186/s12967-015-0532-y.
  9. Fernández M, Bourguignon N, Lux-Lantos V, Libertun C. Neonatal exposure to bisphenol a and reproductive and endocrine alterations resembling the polycystic ovarian syndrome in adult rats.Environ Health Perspect. 2010 Sep;118(9):1217-22. doi: 10.1289/ehp.0901257. Epub 2010 Apr 22.
  10. Li TT, Xu LZ, Chen YH, Deng HM, Liang CY, Liu Y, Liu XF, Zhang J, Kang DY, Qiu DS, Han DW, Hu R. Effects of eight environmental endocrine disruptors on insulin resistance in patients with polycystic ovary syndrome: a preliminary investigation. Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct;31(10):1753-6.
  11. Kandaraki E, Chatzigeorgiou A, Piperi C, Palioura E, Palimeri S, Korkolopoulou P, Koutsilieris M, Papavassiliou AG.Reduced ovarian glyoxalase-I activity by dietary glycotoxins and androgen excess: a causative link to polycystic ovarian syndrome. Mol Med. 2012 Oct 24;18:1183-9. doi: 10.2119/molmed.00293.
  12. Kandaraki E, Chatzigeorgiou A, Piperi C, Palioura E, Palimeri S, Korkolopoulou P, Koutsilieris M, Papavassiliou AG.Reduced ovarian glyoxalase-I activity by dietary glycotoxins and androgen excess: a causative link to polycystic ovarian syndrome. Mol Med. 2012 Oct 24;18:1183-9. doi: 10.2119/molmed.00293.
  13. Tantalaki E, Piperi C, Livadas S, Kollias A, Adamopoulos C, Koulouri A, Christakou C, Diamanti-Kandarakis E. Impact of dietary modification of advanced glycation end products (AGEs) on the hormonal and metabolic profile of women with polycystic ovary syndrome (PCOS). 2014. Hormones (Athens)Jan-Mar;13(1):65-73.
  14. González F. Nutrient-Induced Inflammation in Polycystic Ovary Syndrome: Role in the Development of Metabolic Aberration and Ovarian Dysfunction.Semin Reprod Med. 2015 Jul;33(4):276-86. doi: 10.1055/s-0035-1554918. Epub 2015 Jul 1
  15. Jamnik J, García-Bailo B, Borchers CH, El-Sohemy A. Gluten Intake Is Positively Associated with Plasma α2-Macroglobulin in Young Adults. J Nutr. 2015 Apr 8. pii: jn212829.
  16. Soares FL, de Oliveira Matoso R, Teixeira LG, Menezes Z, Pereira SS, Alves AC, Batista NV, de Faria AM, Cara DC, Ferreira AV, Alvarez-Leite JI. Gluten-free diet reduces adiposity, inflammation and insulin resistance associated with the induction of PPAR-alpha and PPAR-gamma expression. J Nutr Biochem. 2012 Dec 17.
  17. Thomson RL, Spedding S, Buckley JD.Vitamin D in the aetiology and management of polycystic ovary syndrome. Clin Endocrinol (Oxf). 2012 Sep;77(3):343-50. doi: 10.1111/j.1365-2265.2012.04434.x.
  18. Kiałka M, Milewicz T, Klocek M.Blood pressure and polycystic ovary syndrome (PCOS).Przegl Lek. 2015;72(6):309-12.
  19. Wilson JL, Chen W, Dissen GA, Ojeda SR, Cowley MA, Garcia-Rudaz C, Enriori PJ. Excess of nerve growth factor in the ovary causes a polycystic ovary-like syndrome in mice, which closely resembles both reproductive and metabolic aspects of the human syndrome. Endocrinology. 2014 Nov;155(11):4494-506. doi: 10.1210/en.2014-1368. Epub 2014 Sep 11.
  20. Lin AW, Lujan ME. Comparison of Dietary Intake and Physical Activity between Women with and without Polycystic Ovary Syndrome: A Review.Advances in Nutrition. 2014;5(5):486-496. doi:10.3945/an.113.005561.
  21. Ahmadi A, Akbarzadeh M, Mohammadi F, Akbari M, Jafari B, Tolide-Ie HR.Anthropometric characteristics and dietary pattern of women with polycystic ovary syndrome. Indian J Endocrinol Metab. 2013 Jul;17(4):672-6. doi: 10.4103/2230-8210.113759.
  22. Graff SK, Mário FM, Alves BC, Spritzer PM.Dietary glycemic index is associated with less favorable anthropometric and metabolic profiles in polycystic ovary syndrome women with different phenotypes. Fertil Steril. 2013 Oct;100(4):1081-8. doi: 10.1016/j.fertnstert.2013.06.005. Epub 2013 Jul 2.
  23. Barr S, Reeves S, Sharp K, Jeanes YM.An isocaloric low glycemic index diet improves insulin sensitivity in women with polycystic ovary syndrome. J Acad Nutr Diet. 2013 Nov;113(11):1523-31. doi: 10.1016/j.jand.2013.06.347. Epub 2013 Aug 30.
  24. Salama, Amany Alsayed et al. “Anti-Inflammatory Dietary Combo in Overweight and Obese Women with Polycystic Ovary Syndrome.” North American Journal of Medical Sciences 7.7 (2015): 310–316. PMC. Web. 20 Apr. 2016.
  25. Tantalaki E, Piperi C, Livadas S, Kollias A, Adamopoulos C, Koulouri A, Christakou C, Diamanti-Kandarakis E. Impact of dietary modification of advanced glycation end products (AGEs) on the hormonal and metabolic profile of women with polycystic ovary syndrome (PCOS). 2014. Hormones (Athens)Jan-Mar;13(1):65-73.
  26. Khani B, Mehrabian F, Khalesi E, Eshraghi A. Effect of soy phytoestrogen on metabolic and hormonal disturbance of women with polycystic ovary syndrome.J Res Med Sci. 2011 Mar;16(3):297-302.
  27. Faraji R, Sharami SH, Zahiri Z, Asgharni M, Kazemnejad E, Sadeghi S. Evaluation of Relation between Anthropometric Indices and Vitamin D Concentrations in Women with Polycystic Ovarian Syndrome. J Family Reprod Health. 2014 Sep;8(3):123-9.PMID: 25628722
  28. Zadeh-Vakili A, Ramezani Tehrani F, Daneshpour MS, Zarkesh M, Saadat N, Azizi F. Genetic polymorphism of vitamin D receptor gene affects the phenotype of PCOS. Gene. 2013 Feb 15;515(1):193-6. doi: 10.1016/j.gene.2012.11.049. Epub 2012 Dec 13.
  29. Raja-Khan N, Shah J, Stetter CM, Lott ME, Kunselman AR, Dodson WC, Legro RS. High-dose vitamin D supplementation and measures of insulin sensitivity in polycystic ovary syndrome: a randomized, controlled pilot trial. Fertil Steril. 2014 Jun;101(6):1740-6. doi: 10.1016/j.fertnstert.2014.02.021. Epub 2014 Mar 14. PMID: 24636395
  30. Irani M, Seifer DB, Grazi RV, Julka N, Bhatt D, Kalgi B, Irani S, Tal O, Lambert-Messerlian G, Tal R.Vitamin D Supplementation Decreases TGF-β1 Bioavailability in PCOS: A Randomized Placebo-Controlled Trial. J Clin Endocrinol Metab. 2015 Nov;100(11):4307-14. doi: 10.1210/jc.2015-2580. Epub 2015 Oct 20.PMID: 26485217
  31. Irani M, Minkoff H, Seifer DB, Merhi Z.Vitamin D increases serum levels of the soluble receptor for advanced glycation end products in women with PCOS. J Clin Endocrinol Metab. 2014 May;99(5):E886-90. doi: 10.1210/jc.2013-4374. Epub 2014 Feb 27. PMID: 24606102
  32. Asemi Z, Foroozanfard F, Hashemi T, Bahmani F, Jamilian M, Esmaillzadeh A. Calcium plus vitamin D supplementation affects glucose metabolism and lipid concentrations in overweight and obese vitamin D deficient women with polycystic ovary syndrome. Clin Nutr. 2015 Aug;34(4):586-92. doi: 10.1016/j.clnu.2014.09.015. Epub 2014 Oct 3. PMID: 25300649
  33. Firouzabadi Rd, Aflatoonian A, Modarresi S, Sekhavat L, MohammadTaheri S. Therapeutic effects of calcium & vitamin D supplementation in women with PCOS.Complement Ther Clin Pract. 2012 May;18(2):85-8. doi: 10.1016/j.ctcp.2012.01.005. Epub 2012 Feb 20.PMID: 22500844
  34. Pal L, Berry A, Coraluzzi L, Kustan E, Danton C, Shaw J, Taylor H.Therapeutic implications of vitamin D and calcium in overweight women with polycystic ovary syndrome. Gynecol Endocrinol. 2012 Dec;28(12):965-8. doi: 10.3109/09513590.2012.696753. Epub 2012 Jul 11.
  35. Rashidi B1, Haghollahi F, Shariat M, Zayerii F. The effects of calcium-vitamin D and metformin on polycystic ovary syndrome: a pilot study. Taiwan J Obstet Gynecol. 2009 Jun;48(2):142-7. doi: 10.1016/S1028-4559(09)60275-8.
  36. Foroozanfard F, Jamilian M, Jafari Z, Khassaf A, Hosseini A, Khorammian H, Asemi Z. Effects of zinc supplementation on markers of insulin resistance and lipid profiles in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Exp Clin Endocrinol Diabetes. 2015 Apr;123(4):215-20. doi: 10.1055/s-0035-1548790. Epub 2015 Apr 13. PMID: 25868059
  37. Jamilian M, Razavi M, Fakhrie Kashan Z, Ghandi Y, Bagherian T, Asemi Z.Metabolic response to selenium supplementation in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Clin Endocrinol (Oxf). 2015 Jun;82(6):885-91. doi: 10.1111/cen.12699. Epub 2015 Jan 26.PMID: 25510442
  38. Asemi Z, Karamali M, Esmaillzadeh A. Metabolic response to folate supplementation in overweight women with polycystic ovary syndrome: a randomized double-blind placebo-controlled clinical trial. Mol Nutr Food Res. 2014 Jul;58(7):1465-73. doi: 10.1002/mnfr.201400033. Epub 2014 May 15. PMID: 24828019
  39. Bahmani F, Karamali M, Shakeri H, Asemi Z.The effects of folate supplementation on inflammatory factors and biomarkers of oxidative stress in overweight and obese women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled clinical trial. Clin Endocrinol (Oxf). 2014 Oct;81(4):582-7. doi: 10.1111/cen.12451. Epub 2014 Apr 15.PMID: 24628390
  40. Mohammadi E, Rafraf M, Farzadi L, Asghari-Jafarabadi M, Sabour S.Effects of omega-3 fatty acids supplementation on serum adiponectin levels and some metabolic risk factors in women with polycystic ovary syndrome. Asia Pac J Clin Nutr. 2012;21(4):511-8. PMID: 23017309

  41. Cussons AJ, Watts GF, Mori TA, Stuckey BG.Omega-3 fatty acid supplementation decreases liver fat content in polycystic ovary syndrome: a randomized controlled trial employing proton magnetic resonance spectroscopy. J Clin Endocrinol Metab. 2009 Oct;94(10):3842-8. doi: 10.1210/jc.2009-0870. Epub 2009 Jul 21.

     

    Nordio M, Proietti E.The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOS overweight patients compared to myo-inositol supplementation alone.
    Eur Rev Med Pharmacol Sci. 2012 May;16(5):575-81.PMID: 22774396
    (44) Ciotta L, Stracquadanio M, Pagano I, Carbonaro A, Palumbo M, Gulino F.Effects of myo-inositol supplementation on oocyte's quality in PCOS patients: a double blind trial.
    Eur Rev Med Pharmacol Sci. 2011 May;15(5):509-14.PMID: 21744744

  42. Pacchiarotti A, Carlomagno G, Antonini G, Pacchiarotti A. Gynecol Endocrinol.  Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome. 2016 Jan;32(1):69-73. doi: 10.3109/09513590.2015.1101444. Epub 2015 Oct 28.
  43. Li, C., Xing, C., Zhang, J. et al. Une alimentation limitée dans le temps de huit heures améliore les profils endocrinien et métabolique chez les femmes atteintes du syndrome des ovaires polykystiques anovulatoires. J Transl Med 19, 148 (2021). https://doi.org/10.1186/s12967-021-02817-2
  44. Nordio M, Proietti E.The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOS overweight patients compared to myo-inositol supplementation alone. Eur Rev Med Pharmacol Sci. 2012 May;16(5):575-81.PMID: 22774396
     
  45. Ciotta L, Stracquadanio M, Pagano I, Carbonaro A, Palumbo M, Gulino F.Effects of myo-inositol supplementation on oocyte's quality in PCOS patients: a double blind trial. Eur Rev Med Pharmacol Sci. 2011 May;15(5):509-14.PMID: 21744744

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